Research Lines
The nanoBiosystems Group is committed to pioneering advanced, miniaturized diagnostic and therapeutic technologies, translating fundamental scientific discoveries into practical clinical applications. Although our primary focus is on tackling healthcare challenges in gynecology and infertility, our research also addresses wider medical issues, contributing to solutions across diverse fields.
Microfluidic nanobiosensors

Microfluidic nanobiosensors integrated with advanced spectroscopy techniques for enhanced sensitivity in detection.

Microfluidic nanobiosensors integrated with advanced spectroscopy techniques for enhanced sensitivity in detection.
Microrobotic tools

Tethered and untethered microrobotic tools for precise cell manipulation and controlled drug delivery.

Tethered and untethered microrobotic tools for precise cell manipulation and controlled drug delivery.
Smart sensor-actuators

Smart sensor-actuator systems for next-generation organ-on-a-chip platforms.

Smart sensor-actuator systems for next-generation organ-on-a-chip platforms.
Imaging and Advanced Control Systems

In vivo imaging and control for deploying sensing and actuation micro-nanosystems.

In vivo imaging and control for deploying sensing and actuation micro-nanosystems.
Related Publications
The list of publications of our group is periodically updated on the publications section.
Other publications, such as conference proceedings and book chapters are shown bellow:
Smart Surface Engineering in Microcarriers: Towards Applications in Cancer Therapy
Fatemeh Rajabasadi, Silvia Moreno, Mercedes Gonzalez, Pedro Viñola, Kristin Fichna, Franziska Hebenstreit, Susanne Boye, Andreas Janke, Dietmar Appelhans, Mariana Medina-Sánchez (2025)
https://chemrxiv.org/engage/chemrxiv/article-details/67a38cb3fa469535b92920bb
Study of the influence of loss function weights with YOLOv8 and YOLOv9 on the tracking accuracy of medical microrobots
Johanna Hoppe, Richard Nauber, David Castellanos-Robles, Jürgen Czarske, Mariana Medina-Sánchez (2024)
International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)
P-260 In Vitro Fertilization (IVF) using magnetotactic sperm cells and their prospects for assisted in vivo reproduction
C Ribeiro, F Striggow, F Hebenstreit, R Nauber, J Schoen, M Medina-Sanchez (2024/7/1)
Human Reproduction 39 (Supplement_1), deae108. 630
Geometry matters: Gamete transport using magnetic microrobots
David Castellanos Robles, Farzin Akbar, Mariana Medina-Sánchez (2024/1/1)
Academic Press
Sperm-micromotors for assisted reproduction and drug delivery
F Striggow, F Akbar, A Aziz, M Medina-Sánchez
Recent Progress in Medical Miniature Robots
Microrobot's performance in cell-lining surfaces and ex-vivo tissue
Carla Ribeiro, Richard Nauber, Azaam Aziz, David Castellanos-Robles, Mariana Hebenstreit, Franziska, Medina-Sánchez
International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)
Optimization of smart microactuators utilizing 2D and 3D lithography
Sumaiya Tahera Rahman, David Castellanos-Robles, Fatemeh Rajabasadi, Mariana Medina-Sánchez
International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)
Photoacoustics-guided real-time closed-loop control of magnetic microrobots through deep learning
R Nauber, J Hoppe, D Castellanos-Robles, M Medina-Sánchez
International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)
Nanobiosistemas news
Review Article Highlights 25 Years of Modern Near-field Optical Nanoimaging
A newly published review article in Nature Reviews Materials highlights the groundbreaking impact of scattering-type scanning near-field optical microscopy (s-SNOM), a technique that surpasses the diffraction limit to achieve nanoscale optical imaging across a broad spectral range. Authored by leading experts in...Read more